Cytogenetic Technologists

Arrange and attach chromosomes in numbered pairs on karyotype charts, using standard genetics laboratory practices and nomenclature, to identify normal or abnormal chromosomes.

Analyze chromosomes found in biological specimens to aid diagnoses and treatments for genetic diseases such as congenital birth defects, fertility problems, and hematological disorders.

Count numbers of chromosomes and identify the structural abnormalities by viewing culture slides through microscopes, light microscopes, or photomicroscopes.

Create chromosome images using computer imaging systems.

Examine chromosomes found in biological specimens to detect abnormalities.

Select appropriate culturing system or procedure based on specimen type and reason for referral.

Harvest cell cultures using substances such as mitotic arrestants, cell releasing agents, and cell fixatives.

Summarize test results and report to appropriate authorities.

Describe chromosome, FISH and aCGH analysis results in Internations System of Cytogenetic Nomenclature (ISCN) language.

Prepare slides of cell cultures following standard procedures.

Prepare biological specimens such as amniotic fluids, bone marrow, tumors, chorionic villi, and blood, for chromosome examinations.

Recognize and report abnormalities in the color, size, shape, composition, or pattern of cells.

Extract, measure, dilute as appropriate, label, and prepare DNA for array analysis.

Select or prepare specimens and media for cell cultures using aseptic techniques, knowledge of medium components, or cell nutritional requirements.

Input details of specimen processing, analysis, and technical issues into logs or laboratory information systems (LIS).

Apply prepared specimen and control to appropriate grid, run instrumentation, and produce analyzable results.

Select banding methods to permit identification of chromosome pairs.

Stain slides to make chromosomes visible for microscopy.

Input details of specimens into logs or computer systems.

Communicate test results or technical information to patients, physicians, family members, or researchers.

Select appropriate methods of preparation and storage of media to maintain potential of hydrogen (pH), sterility, or ability to support growth.

Develop, implement, and monitor quality control and quality assurance programs to ensure accurate and precise test performance and reports.

Determine optimal time sequences and methods for manual or robotic cell harvests.

Evaluate appropriateness of received specimens for requested tests.

Identify appropriate methods of specimen collection, preservation, or transport.

Communicate to responsible parties unacceptable specimens and suggest remediation for future submissions.

Archive case documentation and study materials as required by regulations and laws.

Supervise subordinate laboratory staff.

Maintain laboratory equipment such as photomicroscopes, inverted microscopes, and standard darkroom equipment.

Develop and implement training programs for trainees, medical students, resident physicians or post-doctoral fellows.